Libertad Asuncion beat Newell's Old Boys 1-3. Newell's Old Boys played with ten from minute 84. Best on the pitch was A. Bareiro, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   ARG 3-4-3·4-4-2 PAR
   Coach: G. Burgos · D. GarneroReferee: E. Ostojich📍 Estadio Marcelo Alberto Bielsa
2. 1. First half
   2. 15'
      ARG
      Yellow card
      Y. Cabral
   3. 20'
      PAR
      Yellow card
      A. Bareiro
   4. 21'
      ARG
      Yellow card
      D. Calcaterra
   5. 32'
      PAR
      Yellow card
      Adrián Martínez
   6. 36'
      PAR
      GOOOAL!Daniel BocanegraAssist: I. Franco
   7. 39'
      ARG
      Yellow card
      Pablo Pérez
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲Juan Sforza▼Mauro Formica
   3. 46'
      ARG
      Substitution
      ▲J. Cacciabue▼F. Nadalín
   4. 46'
      ARG
      Substitution
      ▲F. Negri▼J. Freytes
   5. 46'
      PAR
      Substitution
      ▲R. Bogarin▼Ivan Franco
   6. 55'
      PAR
      GOOOAL!Adrián MartínezAssist: A. Bareiro
   7. 60'
      ARG
      Substitution
      ▲Justo Giani▼J. Marcioni
   8. 68'
      PAR
      Yellow card
      D. Viera
   9. 70'
      PAR
      Substitution
      ▲Héctor Villalba▼S. Ferreira
   10. 74'
       ARG
       Yellow card
       M. Capasso
   11. 79'
       ARG
       Substitution
       ▲Maximiliano Rodríguez▼I. Scocco
   12. 84'
       ARG
       Yellow card
       M. Capasso
   13. 84'
       ARG
       Red card
       M. Capasso
   14. 85'
       PAR
       Substitution
       ▲A. Mejía▼Daniel Bocanegra
   15. 86'
       PAR
       Substitution
       ▲R. Martínez▼Adrián Martínez
   16. 86'
       PAR
       GOOOAL!A. BareiroAssist: D. Viera
   17. 90'
       ARG
       GOOOAL!Maximiliano RodríguezPenalty
   18. 90'
       ARG
       Yellow card
       Pablo Pérez
   19. 90'
       ARG
       Red card
       Pablo Pérez
   20. 90+1'
       PAR
       Substitution
       ▲A. Oviedo▼A. Bareiro