San Lorenzo and 12 de Octubre drew 1-1. San Lorenzo controlled the ball — 67% possession — but had nothing to show for it. Best on the pitch was Óscar Romero, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   ARG 4-3-3·4-4-2 PAR
   Coach: D. Dabove · P. SarabiaReferee: Wilton Pereira Sampaio📍 Estadio Pedro Bidegaín
2. 1. First half
   2. 11'
      PAR
      Yellow card
      F. Manenti
   3. 14'
      ARG
      Yellow card
      V. Salazar
   4. 14'
      ARG
      Substitution
      ▲D. Braghieri▼A. Donatti
   5. 28'
      PAR
      Yellow card
      A. Núñez
   6. 31'
      ARG
      GOOOAL!F. TroyanskyAssist: Ó. Romero
   7. 38'
      ARG
      Yellow card
      Julián Palacios
   8. 45'
      PAR
      GOOOAL!A. NúñezAssist: David Mendieta Alfonso
3. 1. Second half
   2. 62'
      PAR
      Yellow card
      Juan Aguilar
   3. 65'
      ARG
      Substitution
      ▲J. Ramirez▼A. Diaz
   4. 65'
      ARG
      Substitution
      ▲G. Rojas▼B. Pitton
   5. 67'
      PAR
      Substitution
      ▲Diego Ríos▼A. Shuartzman
   6. 67'
      PAR
      Substitution
      ▲J. Marabel▼P. Velázquez
   7. 77'
      PAR
      Yellow card
      Richard Salinas
   8. 81'
      ARG
      Substitution
      ▲M. Herrera▼V. Salazar
   9. 82'
      ARG
      Substitution
      ▲N. Fernandez▼M. Peralta
   10. 82'
       PAR
       Substitution
       ▲M. Paredes▼A. Núñez
   11. 90'
       ARG
       Yellow card
       S. Rosane