Deportes Tolima and Emelec drew 1-1. Best on the pitch was S. Rodríguez, rated 7.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   COL 4-2-3-1·3-5-1-1 ECU
   Coach: H. Torres · Ismael RescalvoReferee: D. Haro📍 Estadio Monumental
2. 1. First half
   2. 12'
      COL
      Yellow card
      J. Campaz
   3. 22'
      COL
      GOOOAL!Sergio MosqueraPenalty
   4. 41'
      ECU
      GOOOAL!A. ZapataAssist: J. Rojas
   5. 45'
      COL
      Yellow card
      Leyvin Balanta
3. 1. Second half
   2. 46'
      COL
      Yellow card
      Jhon Narvaez
   3. 52'
      ECU
      Yellow card
      D. Arroyo
   4. 64'
      ECU
      Substitution
      ▲Jefferson Orejuela▼D. Arroyo
   5. 64'
      ECU
      Substitution
      ▲Jose Francisco Cevallos▼Joao Rojas
   6. 65'
      ECU
      Substitution
      ▲J. G. Rodriguez Perlaza▼Bryan Carabali
   7. 68'
      ECU
      Yellow card
      R. Caicedo
   8. 76'
      COL
      Substitution
      ▲Omar Albornoz▼L. Miranda
   9. 81'
      COL
      Substitution
      ▲J. Hernández▼Andrey Estupinan
   10. 81'
       COL
       Substitution
       ▲J. Ortiz▼G. Ramírez
   11. 87'
       COL
       Yellow card
       J. Ríos
   12. 87'
       COL
       Substitution
       ▲Guillermo Celis▼J. Ríos
   13. 90'
       ECU
       Yellow card
       J. G. Rodriguez Perlaza