Rosario Central beat Huachipato 5-0. Best on the pitch was D. Martinez, rated 8.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   ARG 4-4-2·4-1-4-1 CHI
   Coach: C. González · J. LuveraReferee: C. Ferreyra📍 Estadio Florencio Solá
2. 1. First half
   2. 27'
      ARG
      GOOOAL!L. GambaAssist: D. Martínez
   3. 36'
      ARG
      GOOOAL!E. VecchioPenalty
   4. 37'
      CHI
      Substitution
      ▲J. Gutiérrez▼I. E. Poblete Zuniga
   5. 39'
      CHI
      Yellow card
      C. Martínez
   6. 41'
      CHI
      Yellow card
      W. Mazzantti
   7. 44'
      CHI
      Own goalJ. Gutiérrez
   8. 45+1'
      ARG
      GOOOAL!D. MartinezAssist: D. Zabala
3. 1. Second half
   2. 58'
      ARG
      Yellow card
      D. Martinez
   3. 59'
      CHI
      Substitution
      ▲Á. Garrido▼J. Córdova
   4. 59'
      CHI
      Substitution
      ▲C. Huanca▼W. Mazzantti
   5. 59'
      CHI
      Substitution
      ▲B. Palmezano▼J. Altamirano
   6. 64'
      ARG
      Substitution
      ▲F. Torrent▼D. Martinez
   7. 65'
      ARG
      Substitution
      ▲A. Marinelli▼L. Ferreyra
   8. 71'
      ARG
      Yellow card
      Marco Ruben
   9. 72'
      CHI
      Substitution
      ▲J. Verdugo▼C. Sepúlveda
   10. 73'
       ARG
       Substitution
       ▲G. Infantino▼D. Zabala
   11. 73'
       ARG
       Substitution
       ▲L. Dupuy▼Marco Ruben
   12. 77'
       CHI
       Yellow card
       G. Castellon
   13. 77'
       CHI
       Yellow card
       J. Verdugo
   14. 78'
       ARG
       GOOOAL!L. DupuyAssist: F. Almada
   15. 80'
       ARG
       Substitution
       ▲F. Lo Celso▼E. Vecchio
   16. 89'
       ARG
       Yellow card
       F. Lo Celso