Deportivo Tachira FC and Rosario Central drew 2-2. Best on the pitch was M. Cova, rated 9.2.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   VEN 4-2-3-1·4-4-2 ARG
   Coach: J. Tolisano · C. GonzálezReferee: Flavio Rodrigues De Souza📍 Estadio Polideportivo de Pueblo Nuevo
2. 1. First half
   2. 26'
      ARG
      GOOOAL!L. Ferreyra
3. 1. Second half
   2. 58'
      VEN
      Substitution
      ▲A. Uribe▼L. Gómez
   3. 59'
      VEN
      GOOOAL!Jose Luis GranadosAssist: M. Cova
   4. 69'
      ARG
      Substitution
      ▲R. Villagra▼E. Ojeda
   5. 74'
      VEN
      Substitution
      ▲D. Angarita▼E. Pérez Greco
   6. 74'
      ARG
      Substitution
      ▲N. Ferreyra▼G. Avila
   7. 79'
      VEN
      Substitution
      ▲M. Fernández▼Y. Chacón
   8. 81'
      ARG
      Substitution
      ▲L. Dupuy▼L. Gamba
   9. 82'
      ARG
      Substitution
      ▲A. Marinelli▼Marco Ruben
   10. 90'
       ARG
       GOOOAL!A. MarinelliAssist: L. Martínez
   11. 90+4'
       VEN
       GOOOAL!D. AngaritaAssist: M. Cova