Santos beat Universidad Catolica 3-2. Best on the pitch was Léo Baptistão, rated 7.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   BRA 4-4-2·4-3-3 ECU
   Coach: F. Bustos · M. RondelliReferee: J. Argote📍 Estádio Urbano Caldeira
2. 1. First half
   2. 7'
      BRA
      Yellow card
      Willian Maranhão
   3. 15'
      BRA
      GOOOAL!Jhojan JulioAssist: Mádson
   4. 26'
      ECU
      GOOOAL!Cristian MartínezAssist: I. Díaz
   5. 42'
      ECU
      GOOOAL!Kevin Minda
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Vinicius Zanocelo▼Willian Maranhão
   3. 53'
      BRA
      Substitution
      ▲Ângelo▼Lucas Braga
   4. 66'
      BRA
      Substitution
      ▲Léo Baptistão▼Ricardo Goulart
   5. 69'
      ECU
      Substitution
      ▲Anderson Ordóñez▼Cristian Martínez
   6. 72'
      ECU
      Yellow card
      W. Cevallos
   7. 72'
      ECU
      Substitution
      ▲W. Cevallos▼S. Zamora
   8. 77'
      ECU
      Yellow card
      Y. Mosquera
   9. 78'
      BRA
      GOOOAL!Léo BaptistãoPenalty
   10. 80'
       ECU
       Yellow card
       F. Martinez
   11. 82'
       BRA
       Substitution
       ▲Lucas Barbosa▼Jhojan Julio
   12. 82'
       BRA
       Substitution
       ▲Gabriel Pirani▼Rodrigo Fernandez
   13. 85'
       BRA
       GOOOAL!B. AnguloAssist: Lucas Barbosa
   14. 87'
       ECU
       Substitution
       ▲R. Rivas▼G. Cortez