Santos beat Universidad Catolica 0-1. Universidad Catolica controlled the ball — 66% possession — but had nothing to show for it. Best on the pitch was Camacho, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   ECU 4-3-3·4-3-3 BRA
   Coach: M. Rondelli · F. BustosReferee: G. Vargas📍 Estadio Olímpico Atahualpa
2. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Lucas Braga▼Lucas Barbosa
   3. 61'
      BRA
      Substitution
      ▲Rwan Cruz▼B. Angulo
   4. 61'
      BRA
      Substitution
      ▲Marcos Leonardo▼Gabriel Pirani
   5. 63'
      ECU
      Substitution
      ▲W. Chalá▼D. Clavijo
   6. 68'
      ECU
      Yellow card
      Y. Mosquera
   7. 72'
      ECU
      Substitution
      ▲W. Cevallos▼F. Martinez
   8. 72'
      BRA
      Substitution
      ▲Lucas Pires▼Willian Maranhão
   9. 85'
      ECU
      Substitution
      ▲M. Carrasco▼G. Anangono
   10. 85'
       ECU
       Substitution
       ▲R. Rivas▼Ismael Díaz
   11. 86'
       BRA
       Substitution
       ▲Vinicius Zanocelo▼Camacho
   12. 90+1'
       BRA
       GOOOAL!Rwan CruzAssist: Lucas Pires