Independiente beat Deportivo La Guaira 4-0. L. Benegas scored 2 goals. Best on the pitch was J. Aramburu, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   ARG 4-3-3·3-4-2-1 VEN
   Coach: E. Domínguez · D. FaríasReferee: J. Burgos📍 Estadio Libertadores de América
2. 1. First half
   2. 11'
      VEN
      Yellow card
      JMJon Mikel Aramburu Mejias
   3. 31'
      ARG
      Yellow card
      A. Vigo
   4. 41'
      VEN
      Own goalY. Cumana
   5. 43'
      ARG
      Yellow card
      T. A. Pozzo
3. 1. Second half
   2. 47'
      ARG
      GOOOAL!L. Benegas
   3. 53'
      VEN
      Substitution
      ▲H. García▼Y. Rivas
   4. 61'
      ARG
      Substitution
      ▲Leandro Fernandez▼C. Benavídez
   5. 68'
      ARG
      Substitution
      ▲G. Togni▼L. Rodriguez
   6. 68'
      ARG
      Substitution
      ▲Andrés Roa▼T. A. Pozzo
   7. 71'
      VEN
      Substitution
      ▲Jose Rivas▼S. Herrera
   8. 72'
      VEN
      Substitution
      ▲S. Unrein▼Jovanny Bolívar
   9. 77'
      ARG
      Substitution
      ▲L. Gonzalez▼J. Cazares
   10. 83'
       ARG
       GOOOAL!Andrés RoaAssist: L. Fernández
   11. 85'
       ARG
       Yellow card
       L. Benegas
   12. 85'
       VEN
       Yellow card
       A. Flores
   13. 86'
       VEN
       Yellow card
       Jose Rivas
   14. 90'
       ARG
       GOOOAL!L. BenegasAssist: L. Fernández