Antofagasta beat Defensa y Justicia 0-2. Defensa y Justicia controlled the ball — 70% possession — but had nothing to show for it. Best on the pitch was D. Sanchez, rated 8.2.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   ARG 4-2-3-1·4-4-2 CHI
   Coach: S. Beccacece · D. RevecoReferee: M. Díaz de Vivar📍 Estadio Norberto Tito Tomaghello
2. 1. First half
   2. 42'
      CHI
      GOOOAL!B. HurtadoAssist: F. Bravo
3. 1. Second half
   2. 53'
      CHI
      Yellow card
      S. Cordero
   3. 57'
      CHI
      Substitution
      ▲P. Magalhaes▼D. Orellana
   4. 59'
      CHI
      Yellow card
      C. Rodríguez
   5. 67'
      CHI
      Substitution
      ▲M. Sánchez▼S. Cordero
   6. 67'
      CHI
      Substitution
      ▲Byron Nieto▼C. Rodríguez
   7. 72'
      ARG
      Substitution
      ▲H. Fernández▼A. Fontana
   8. 73'
      CHI
      Yellow card
      J. Flores
   9. 73'
      CHI
      GOOOAL!M. LópezAssist: B. Hurtado
   10. 74'
       ARG
       Substitution
       ▲B. Cuello▼Alexis Soto
   11. 79'
       CHI
       Yellow card
       B. Hurtado
   12. 79'
       CHI
       Substitution
       ▲S. González▼B. Hurtado
   13. 79'
       CHI
       Substitution
       ▲E. Ahumada▼J. Flores
   14. 81'
       ARG
       Substitution
       ▲R. Loaiza▼J. Rodriguez
   15. 81'
       ARG
       Substitution
       ▲M. Duarte▼N. Tripichio
   16. 82'
       CHI
       Yellow card
       D. Sanchez
   17. 84'
       CHI
       Yellow card
       Marco Collao Ramos