General Caballero beat Deportivo La Guaira 0-1. Deportivo La Guaira controlled the ball — 71% possession — but had nothing to show for it. Best on the pitch was L. Guillén, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   VEN 5-3-2·4-2-3-1 PAR
   Coach: D. Farías · L. TheilerReferee: R. Pérez📍 Estadio Olímpico de la UCV
2. 1. First half
   2. 8'
      VEN
      Yellow card
      J. Ramos
   3. 32'
      PAR
      GOOOAL!K. Fernández
3. 1. Second half
   2. 60'
      PAR
      Yellow card
      GAG. D. Bordon Alvarenga
   3. 60'
      VEN
      Substitution
      ▲S. Unrein▼K. Lamadrid
   4. 62'
      PAR
      Substitution
      ▲S. Benítez▼L. Fernández
   5. 62'
      PAR
      Substitution
      ▲Á. Recalde▼G. Bordón
   6. 65'
      PAR
      Yellow card
      J. Vera
   7. 72'
      PAR
      Substitution
      ▲H. Lezcano▼L. Barrios
   8. 78'
      VEN
      Substitution
      ▲Guillermo Marín▼S. Herrera
   9. 78'
      VEN
      Substitution
      ▲Rommell Ibarra▼Kendrys Silva
   10. 88'
       PAR
       Substitution
       ▲E. Llanes▼C. Gavilán
   11. 88'
       PAR
       Substitution
       ▲J. Aldama▼K. Fernández