Deportivo Cali and FBC Melgar drew 0-0. Deportivo Cali played with ten from minute 86. Best on the pitch was C. Caceda, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   COL 4-2-3-1·4-2-3-1 PER
   Coach: R. Dudamel · N. LorenzoReferee: M. Díaz de Vivar📍 Estadio Deportivo Cali
2. 1. First half
   2. 19'
      COL
      Yellow card
      Y. Congo
   3. 45'
      PER
      Yellow card
      P. Reyna
3. 1. Second half
   2. 46'
      PER
      Substitution
      ▲K. Quevedo▼M. Pérez Guedes
   3. 52'
      COL
      Yellow card
      K. Velasco
   4. 55'
      PER
      Yellow card
      H. Orzán
   5. 58'
      COL
      Substitution
      ▲Christian Mafla▼H. Mosquera
   6. 58'
      COL
      Substitution
      ▲E. Camargo▼Carlos Robles
   7. 71'
      COL
      Substitution
      ▲C. Lucumi▼A. Rodríguez
   8. 79'
      COL
      Substitution
      ▲D. Luna▼Teófilo Gutiérrez
   9. 79'
      COL
      Substitution
      ▲J. Mina▼A. Gutiérrez
   10. 84'
       COL
       VAR review
       C. Lucumi
   11. 86'
       COL
       Red card
       C. Lucumi
   12. 88'
       COL
       VAR review
       D. Luna
   13. 89'
       COL
       Red card
       D. Luna
   14. 90'
       PER
       Substitution
       ▲Joel Sánchez▼W. Tandazo
   15. 90+5'
       PER
       Yellow card
       Joel Sánchez
   16. 90+7'
       PER
       Substitution
       ▲B. Portugal▼A. Arias