Deportivo Tachira FC and Santos drew 1-1. Best on the pitch was João Paulo, rated 7.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   VEN 4-2-3-1·4-3-3 BRA
   Coach: Álex Pallarés · F. BustosReferee: G. Vargas📍 Estadio Polideportivo de Pueblo Nuevo
2. 1. First half
   2. 11'
      VEN
      Yellow card
      Francisco Flores
   3. 25'
      BRA
      Yellow card
      Vinicius
   4. 30'
      BRA
      Own goalVinicius Zanocelo
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Auro▼Vinicius
   3. 56'
      BRA
      Substitution
      ▲Rwan Cruz▼Ângelo
   4. 56'
      BRA
      Substitution
      ▲Carlos Sánchez▼Vinicius Zanocelo
   5. 69'
      VEN
      Substitution
      ▲Richard Figueroa▼Robert Hernandez
   6. 69'
      BRA
      Substitution
      ▲Willian Maranhão▼Camacho
   7. 69'
      BRA
      Substitution
      ▲Lucas Braga▼Jhojan Julio
   8. 74'
      VEN
      Substitution
      ▲Edder Farias▼A. Uribe
   9. 86'
      BRA
      GOOOAL!B. AnguloAssist: C. Sánchez
   10. 89'
       VEN
       Substitution
       ▲M. Fernández▼Y. Chacón
   11. 89'
       VEN
       Substitution
       ▲R. Simisterra▼R. Garcés
   12. 90+2'
       VEN
       Yellow card
       J. Marrufo