Defensa y Justicia beat Penarol 0-3. Best on the pitch was G. Togni, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2023
   URU 4-2-3-1·4-2-3-1 ARG
   Coach: A. Arias · J. VaccariReferee: F. Gilabert📍 Estadio Campeón del Siglo
2. 1. First half
   2. 29'
      URU
      Yellow card
      M. Arezo
   3. 42'
      ARG
      GOOOAL!G. Togni
3. 1. Second half
   2. 46'
      URU
      Substitution
      ▲N. Rossi▼K. Méndez
   3. 50'
      ARG
      GOOOAL!N. FernandezAssist: J. López
   4. 53'
      ARG
      Yellow card
      K. Gutierrez
   5. 55'
      ARG
      VAR review
      K. Gutierrez
   6. 62'
      URU
      Substitution
      ▲M. Alonso▼Carlos Sánchez
   7. 65'
      URU
      Yellow card
      M. Alonso
   8. 67'
      URU
      Yellow card
      N. Rossi
   9. 68'
      URU
      Yellow card
      H. Menosse
   10. 69'
       URU
       Substitution
       ▲Diego Rolán▼S. Rodríguez
   11. 69'
       URU
       Substitution
       ▲B. Guisolfo▼R. A. Saravia Salvia
   12. 76'
       ARG
       Yellow card
       Alexis Soto
   13. 77'
       ARG
       Substitution
       ▲Santiago Solari▼G. Alanis
   14. 77'
       ARG
       Substitution
       ▲N. Tripichio▼J. Lopez
   15. 81'
       ARG
       Substitution
       ▲J. Malatini▼Nazareno Colombo
   16. 85'
       URU
       Substitution
       ▲Y. Rak▼H. Menosse
   17. 87'
       ARG
       GOOOAL!Santiago SolariAssist: A. Soto
   18. 88'
       ARG
       VAR review
       E. Unsain
   19. 90'
       ARG
       Substitution
       ▲L. T. Escalante▼N. Fernandez
   20. 90'
       ARG
       Substitution
       ▲J. B. Miritello▼K. Gutierrez
   21. 90+5'
       URU
       Yellow card
       Y. Rak