Independiente beat Boston River 2-1. The winner had to work for it: 2 from 18 shots. P. Galdames scored 2 goals. Best on the pitch was P. Galdames, rated 8.2.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2025
   ARG 4-3-3·— URU
   Coach: Julio César Vaccari · —Referee: Bruno Arleu de Araujo, Brazil📍 Estadio Libertadores de América
2. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲P. Galdames▼F. Vera
   3. 46'
      ARG
      Substitution
      ▲Lautaro Millán▼S. Hidalgo
   4. 52'
      URU
      Yellow card
      J. Acosta
   5. 58'
      ARG
      Yellow card
      P. Galdames
   6. 61'
      ARG
      GOOOAL!P. GaldamesAssist: G. Avalos
   7. 71'
      URU
      Substitution
      ▲F. Noguera▼F. Chiappini
   8. 71'
      URU
      Substitution
      ▲F. Munoa▼G. Viera
   9. 74'
      ARG
      Substitution
      ▲D. Tarzia▼S. Montiel
   10. 80'
       ARG
       Substitution
       ▲I. Maestro▼Gabriel Ávalos
   11. 81'
       URU
       Substitution
       ▲A. Silva▼A. Anello
   12. 81'
       URU
       Substitution
       ▲F. Suarez▼J. Acosta
   13. 86'
       URU
       GOOOAL!F. Munoa
   14. 89'
       URU
       Substitution
       ▲Valentin Adamo▼A. González
   15. 90'
       ARG
       GOOOAL!P. GaldamesAssist: F. Loyola
   16. 90+3'
       ARG
       Yellow card
       Felipe Loyola
   17. 90+3'
       ARG
       Yellow card
       K. Lomonaco
   18. 90+3'
       URU
       Yellow card
       Valentin Adamo
   19. 90+4'
       ARG
       Substitution
       ▲Rodrigo Fernandez▼Leandro Cabral