Godoy Cruz beat Sportivo Luqueno 0-1. The winner had to work for it: 1 from 18 shots. Best on the pitch was L. Arce, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2025
   PAR 4-2-3-1·4-2-3-1 ARG
   Coach: Júlio César Cáceres López · Walter Darío RibonettoReferee: Byran Loayza, Ecuador📍 Estadio Tigo La Huerta
2. 1. First half
   2. 16'
      PAR
      Yellow card
      W. Rodríguez
3. 1. Second half
   2. 46'
      PAR
      Substitution
      ▲Guillermo Hauche▼B. Ayala
   3. 46'
      PAR
      Substitution
      ▲W. González▼Diego Ríos
   4. 47'
      PAR
      Yellow card
      Á. Benítez
   5. 61'
      PAR
      Yellow card
      E. Vera
   6. 65'
      ARG
      Substitution
      ▲A. Auzmendi▼D. Barrea
   7. 72'
      ARG
      GOOOAL!A. AuzmendiAssist: V. Poggi
   8. 74'
      PAR
      Substitution
      ▲L. Comas▼Federico Santander
   9. 80'
      PAR
      Substitution
      ▲F. Benitez▼Á. Benítez
   10. 81'
       PAR
       Yellow card
       L. Comas
   11. 82'
       ARG
       Yellow card
       L. Quiroz
   12. 82'
       ARG
       Substitution
       ▲B. Leyes▼G. Abrego
   13. 82'
       ARG
       Substitution
       ▲T. A. Pozzo▼Facundo Altamira
   14. 84'
       PAR
       Substitution
       ▲M. Pérez▼E. Vera
   15. 89'
       PAR
       Yellow card
       F. Benitez
   16. 90'
       ARG
       Substitution
       ▲K. Parzajuk▼S. Andino
   17. 90+3'
       ARG
       Yellow card
       Vicente Poggi