Universidad Catolica beat Cerro Largo 1-3. Ismael Díaz scored 2 goals. Best on the pitch was Ismael Díaz, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2025
   URU —·4-3-3 ECU
   Coach: — · Diego Andrés Martínez CarreraReferee: Ivo Nigel Mendez Chavez, Bolivia📍 Estadio Centenario
2. 1. First half
   2. 21'
      ECU
      GOOOAL!B. PalaciosAssist: J. Lara
   3. 27'
      URU
      Yellow card
      A. Assis
   4. 32'
      ECU
      GOOOAL!Ismael DíazAssist: M. Diaz
   5. 35'
      URU
      Yellow card
      N. Bertochi
   6. 40'
      ECU
      Yellow card
      D. Romero
   7. 43'
      ECU
      Yellow card
      A. Londono
3. 1. Second half
   2. 46'
      URU
      Substitution
      ▲J. Contrera▼F. Peraza
   3. 46'
      URU
      Substitution
      ▲F. Rossi▼A. Assis
   4. 46'
      URU
      Substitution
      ▲L. Otormín▼A. García
   5. 46'
      URU
      Substitution
      ▲L. Correa▼M. Brasil
   6. 46'
      URU
      Substitution
      ▲A. Di Pippa▼M. Mir
   7. 60'
      URU
      Yellow card
      L. Correa
   8. 61'
      URU
      Yellow card
      M. Añasco
   9. 67'
      ECU
      Substitution
      ▲José Fajardo▼B. Palacios
   10. 74'
       ECU
       Substitution
       ▲A. Rodriguez▼M. Díaz
   11. 76'
       ECU
       VAR review
       Ismael Díaz
   12. 88'
       ECU
       GOOOAL!Ismael Díaz
   13. 90'
       URU
       GOOOAL!M. Añasco
   14. 90+2'
       ECU
       Substitution
       ▲D. Clavijo▼J. Cacciabue
   15. 90+2'
       ECU
       Substitution
       ▲M. Maciel▼L. Moreno
   16. 90+2'
       ECU
       Substitution
       ▲R. Troya▼A. Londono