Once Caldas beat San Antonio Bulo Bulo 0-3. San Antonio Bulo Bulo played with ten from minute 43. Best on the pitch was P. Gomez, rated 8.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2025
   BOL 4-3-3·4-1-4-1 COL
   Coach: Pedro Depablos · Hernán Darío Herrera RamírezReferee: Augusto Bergelio Aragon Bautista, Ecuador📍 Felix Capriles
2. 1. First half
   2. 42'
      BOL
      VAR review
      E. Sánchez
   3. 43'
      BOL
      Red card
      E. Sánchez
3. 1. Second half
   2. 48'
      COL
      Yellow card
      J. Cuesta
   3. 50'
      COL
      GOOOAL!Jefry Zapata
   4. 55'
      BOL
      Substitution
      ▲L. Justiniano▼A. Terrazas
   5. 55'
      BOL
      Substitution
      ▲Hernán Rodríguez▼M. Alonso
   6. 61'
      COL
      Substitution
      ▲P. Gomez▼Michael Barrios
   7. 61'
      COL
      Substitution
      ▲Luis Palacios▼J. Cuesta
   8. 64'
      BOL
      Substitution
      ▲Alonso Sánchez▼L. Barboza
   9. 70'
      COL
      Substitution
      ▲J. Castano▼J. Cardona
   10. 70'
       COL
       Substitution
       ▲Dayro Moreno▼Jefry Zapata
   11. 70'
       COL
       Substitution
       ▲D. Quinones▼M. Zuleta
   12. 73'
       BOL
       Substitution
       ▲R. Lopez▼A. Vasquez
   13. 73'
       BOL
       Substitution
       ▲A. Avalos▼J. Montenegro
   14. 77'
       COL
       Yellow card
       J. Patino
   15. 85'
       COL
       GOOOAL!Dayro MorenoAssist: P. Gomez
   16. 88'
       COL
       GOOOAL!P. GomezAssist: D. Quinones