Independiente del Valle beat Mushuc Runa SC 1-0. The winner had to work for it: 1 from 20 shots. Best on the pitch was G. Cortez, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2025
   ECU 4-3-3·4-4-1-1 ECU
   Coach: Javier Rabanal Hernández · Angeles Paúl Vélez OrdoñezReferee: Gery Vargas, Bolivia📍 Estadio Banco De Guayaquil
2. 1. First half
   2. 13'
      ECU
      Yellow card
      P. Mercado
   3. 19'
      ECU
      GOOOAL!C. SpinelliAssist: P. Mercado
   4. 21'
      ECU
      Yellow card
      Glendys Mina
   5. 30'
      ECU
      Yellow card
      Á. Gracia
3. 1. Second half
   2. 46'
      ECU
      Substitution
      ▲R. Burbano▼J. Verges
   3. 56'
      ECU
      Yellow card
      M. Carabajal
   4. 62'
      ECU
      Substitution
      ▲A. Ibarra▼P. Mercado
   5. 65'
      ECU
      Yellow card
      S. Tapiero
   6. 71'
      ECU
      Yellow card
      R. Burbano
   7. 71'
      ECU
      Substitution
      ▲C. Penilla▼Glendys Mina
   8. 72'
      ECU
      Substitution
      ▲J. Chalá▼Á. Gracia
   9. 82'
      ECU
      Substitution
      ▲B. Delgado▼Carlos Orejuela
   10. 83'
       ECU
       Yellow card
       Darwin Guagua
   11. 83'
       ECU
       Substitution
       ▲J. Mendez▼D. Guagua
   12. 83'
       ECU
       Substitution
       ▲L. Arce▼S. Tapiero
   13. 88'
       ECU
       Substitution
       ▲J. Sornoza▼J. Cazares
   14. 90'
       ECU
       Yellow card
       C. Penilla