Santamarina and Instituto drew 0-0.

1. 0'
   ⚽Kick-off
   Primera Nacional 2021
   Coach: H. Arzubialde · M. VázquezReferee: D. Ceballos📍 Estadio Municipal General San Martín de Tandil
2. 1. First half
   2. 28'
      ARG
      Yellow card
      L. Arregui
3. 1. Second half
   2. 66'
      ARG
      Substitution
      ▲T. Beltrán▼M. Alustiza
   3. 70'
      ARG
      Substitution
      ▲G. Villarruel▼F. N. Watson
   4. 70'
      ARG
      Substitution
      ▲D. Arce▼I. Huguenet
   5. 76'
      ARG
      Substitution
      ▲B. Maidana▼M. Michel
   6. 76'
      ARG
      Substitution
      ▲G. Vernetti▼J. Juárez
   7. 78'
      ARG
      Yellow card
      F. Leiva
   8. 81'
      ARG
      Yellow card
      R. Garro
   9. 88'
      ARG
      Substitution
      ▲T. Allende▼R. Garro
   10. 88'
       ARG
       Substitution
       ▲J. Mateo▼J. Molina
   11. 89'
       ARG
       Yellow card
       T. Beltran