Barcelona SC and Santa Fe drew 2-2. Horacio Romero scored 2 goals.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 1961
   Referee: Ovidio Orrego📍 El Coloso de la Avenida de Las AméricasAttendance: 15,000
2. 1. First half
   2. 10'
      COL
      GOOOAL!APAlberto Perazzo
3. 1. Second half
   2. 46'
      ECU
      GOOOAL!HRHoracio Romero
   3. 50'
      COL
      GOOOAL!OPOsvaldo Panzutto
   4. 58'
      ECU
      GOOOAL!HRHoracio Romero