Cerro Porteno and Club Nacional drew 2-2. Celino Mora scored 2 goals.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 1964
   Referee: Adolfo Reginato📍 UENO El BosqueAttendance: 20,000
2. 1. First half
   2. 36'
      URU
      GOOOAL!MMMario Méndez
3. 1. Second half
   2. 46'
      PAR
      GOOOAL!CMCelino Mora
   3. 50'
      PAR
      GOOOAL!CMCelino Mora
   4. 55'
      URU
      GOOOAL!JOJorge Oyarbide