Penarol beat Emelec 4-1. Héctor Silva scored 2 goals.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 1966
   Referee: Jaime Amor📍 CentenarioAttendance: 18,000
2. 1. First half
   2. 39'
      URU
      GOOOAL!HSHéctor Silva
3. 1. Second half
   2. 56'
      URU
      GOOOAL!HSHéctor Silva
   3. 65'
      URU
      GOOOAL!EAEnrique Alfano
   4. 80'
      ECU
      GOOOAL!JBJorge Bolaños
   5. 88'
      URU
      GOOOAL!EAEnrique Alfano