Club Nacional and Banfield drew 2-2. James Rodriguez scored 2 goals.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2010
   Referee: Heber Lopes📍 Gran Parque CentralAttendance: 34,468
2. 1. First half
   2. 5'
      URU
      GOOOAL!GVGustavo Varela
   3. 18'
      ARG
      GOOOAL!JRJames Rodriguez
   4. 35'
      ARG
      GOOOAL!JRJames RodriguezPenalty
   5. 41'
      URU
      GOOOAL!MRMario Regueiro