River Plate beat Trujillanos FC 4-3. Andrés D'Alessandro scored 2 goals.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2016
   Referee: Víctor Carrillo📍 El MonumentalAttendance: 40,000
2. 1. First half
   2. 9'
      ARG
      GOOOAL!ADAndrés D'Alessandro
   3. 19'
      ARG
      GOOOAL!ADAndrés D'AlessandroPenalty
   4. 30'
      VEN
      GOOOAL!MCMaurice Cova
3. 1. Second half
   2. 49'
      ARG
      GOOOAL!Camilo Mayada
   3. 71'
      ARG
      GOOOAL!LALucas Alario
   4. 74'
      VEN
      GOOOAL!FGFranklin González
   5. 78'
      VEN
      GOOOAL!JCJames CabezasPenalty