Independiente and Santos drew 1-1. Independiente played with ten from minute 62. Best on the pitch was João Paulo, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   ARG 4-2-3-1·4-2-3-1 BRA
   Coach: J. Falcioni · Fernando DinizReferee: D. Haro📍 Estadio Libertadores de América
2. 1. First half
   2. 17'
      BRA
      Yellow card
      Jean Mota
   3. 28'
      ARG
      Yellow card
      D. Blanco
   4. 35'
      ARG
      Yellow card
      L. Romero
   5. 38'
      BRA
      GOOOAL!Kaio Jorge
   6. 44'
      ARG
      Yellow card
      S. Barreto
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲J. Herrera▼D. Blanco
   3. 46'
      ARG
      Substitution
      ▲L. Gonzalez▼Andrés Roa
   4. 62'
      ARG
      Red card
      Juan M. Insaurralde
   5. 68'
      BRA
      Substitution
      ▲Vinicius Zanocelo▼Jean Mota
   6. 68'
      ARG
      GOOOAL!L. Gonzalez
   7. 75'
      BRA
      Substitution
      ▲Lucas Braga▼Marinho
   8. 75'
      BRA
      Substitution
      ▲Gabriel Pirani▼Carlos Sánchez
   9. 77'
      BRA
      Yellow card
      Kaiky
   10. 80'
       ARG
       Substitution
       ▲A. Soñora▼L. Rodriguez
   11. 84'
       ARG
       Substitution
       ▲R. L. Marquez De Meneses▼S. Palacios
   12. 85'
       ARG
       Substitution
       ▲B. Martinez▼A. Velasco
   13. 86'
       BRA
       Substitution
       ▲Marcos Leonardo▼Marcos Guilherme
   14. 86'
       BRA
       Substitution
       ▲Alison▼Camacho
   15. 90'
       ARG
       Yellow card
       S. Barreto
   16. 90'
       ARG
       Red card
       S. Barreto