Rosario Central beat Deportivo Tachira FC 1-0. The winner had to work for it: 1 from 27 shots. Best on the pitch was E. Vecchio, rated 9.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   ARG 4-4-2·4-2-2-2 VEN
   Coach: C. González · J. TolisanoReferee: D. Fedorczuk📍 Estadio Dr. Lisandro de la Torre
2. 1. First half
   2. 42'
      ARG
      GOOOAL!E. VecchioAssist: Luciano Ismael Ferreyra
3. 1. Second half
   2. 46'
      VEN
      Substitution
      ▲E. Pérez Greco▼F. Góndola
   3. 62'
      VEN
      Substitution
      ▲Juan Colina▼Francisco Flores
   4. 62'
      VEN
      Substitution
      ▲E. García▼Y. Chacón
   5. 63'
      ARG
      Yellow card
      G. Avila
   6. 69'
      ARG
      Yellow card
      F. Almada
   7. 75'
      VEN
      Yellow card
      Jose Luis Granados
   8. 75'
      VEN
      Substitution
      ▲D. Angarita▼A. Uribe
   9. 81'
      VEN
      Substitution
      ▲L. Gómez▼D. Zalzman
   10. 82'
       ARG
       Substitution
       ▲A. Veliz▼A. Marinelli
   11. 88'
       ARG
       Substitution
       ▲R. Villagra▼L. Dupuy
   12. 90'
       VEN
       Yellow card
       E. García