Wanderers beat Cerro Largo 0-1. The winner had to work for it: 1 from 13 shots. Best on the pitch was N. Quagliata, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2022
   URU 4-4-2·4-2-3-1 URU
   Coach: L. Núñez · D. CarreñoReferee: K. Ortega📍 Estadio Centenario
2. 1. First half
   2. 26'
      URU
      Yellow card
      Jonathan Ramis
3. 1. Second half
   2. 53'
      URU
      Substitution
      ▲Jorge Benguché▼Jonathan Ramis
   3. 63'
      URU
      GOOOAL!L. PaisAssist: K. Rolón
   4. 64'
      URU
      Substitution
      ▲M. Enrique▼Robert Ergas
   5. 64'
      URU
      Substitution
      ▲G. Machado▼L. Casiani
   6. 65'
      URU
      Substitution
      ▲C. Tizón▼Leandro Onetto
   7. 66'
      URU
      Yellow card
      M. Enrique
   8. 69'
      URU
      Substitution
      ▲D. Riolfo▼E. Tellechea
   9. 69'
      URU
      Substitution
      ▲M. Mendez▼C. Bravo
   10. 70'
       URU
       Substitution
       ▲B. Cordara▼Emiliano Villar
   11. 77'
       URU
       Yellow card
       A. Max
   12. 80'
       URU
       Yellow card
       M. Gianoli
   13. 88'
       URU
       Substitution
       ▲G. Wagner▼N. Quagliata
   14. 88'
       URU
       Substitution
       ▲M. Fracchia▼K. Rolón
   15. 90+3'
       URU
       Yellow card
       L. Pais
   16. 90+3'
       URU
       Substitution
       ▲J. Lacerda▼H. Rivero